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            目錄肽產(chǎn)品
            OREX-002B
            Orexin B, human
            Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
            Size:1.0
            P1(RMB):1011
            MW:2898.39
            One letter sequence:RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
            Molecular Formula:C123H212N44O35S1
            Description:Hypothalamic neuropeptide that regulates feeding behavior, significantly augments food intake in a dose-dependent manner when a bolus was administered intracerebroventricularly. After a 48 hour fast, hypothalamic prepro-orexin mRNA level is up-regulated 2.4. The discovery of Orexins and their receptors may provide a novel molecular basis for understanding the role of the lateral hypothalamic areas in the regulation of energy homeostasis.
            Literature Reference:M.W. Schwartz, Nature Med<$>., 4, 385 (1998); \nT. Sakurai et al., Cell, 92, 573 (1998)
            Cas:
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