Size：1.0
P1(RMB)：582
MW：1093.2?
One letter sequence：Mca-PLA-Nva-Dap(Dnp)-AR-NH2
Molecular Formula：C49H68N14O15
Description：Sensitive substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. When cleaved at the Gly-Leu bond it separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher and results in the increase of fluorescence intensity. The kcat/km value for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7?105 and 6.3?105 M-1s-1, respectively.
Literature Reference：G. Murphy, et al., J. Biol. Chem. 269, 6632 (1994).
Cas：