Size：1.0
P1(RMB)：215
MW：920.2
One letter sequence：IMQVPFSV
Molecular Formula：C43H69N9O11S1
Description：Peptide that contains modified sequence of the gp 100 epitope gp(209-217), in which a methionine replaced the natural threonine at position 2. This peptide also binds to the HLA-A2 molecule with greater affinity than the unmodified peptide and has exhibited a good ability to stimulate melonomareactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide holds promise for the development of novel cancer immunotherapies.
Literature Reference：S.A. Rosenberg et al., Nature Med<$>., 4, 321 (1998)
Cas：