Size：0.5
P1(RMB)：92
MW：767.8
One letter sequence：Z-DEVD-AMC
Molecular Formula：C36H41N5O14
Description：AMC (7-amino-4-methylcoumarin) derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm. Caspase-3 and caspase-7 substrates\n
Literature Reference：Koeplinger KA, et al. (2000). Protein Expr Purif 18, 378-87; \nGarcia-Calvo M, et al. (1998). J Biol Chem 273, 32608-13; \nThornberry NA, et al. (1997). J Biol Chem 272, 17907-11; \nRano TA, et al. (1997). Chem Biol 4, 149-55; \nMargolin N, et al. (1997). J Biol Chem 272, 7223-8; \nMizushima N, et al. (1996). FEBS Lett 395, 267-71; \nFaubion WA, et al. (1999). J Clin Invest 103, 137-45.
Cas：