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            目錄肽產(chǎn)品
            CASP-027B
            Caspase-1 Substrate V, Fluorogenic
            Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)
            Size:1.0
            P1(RMB):582
            MW:1145.2
            One letter sequence:Mca-YVADAP-Lys(DNP)
            Molecular Formula:C53H64N10O19
            Description:Highly fluorescent substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of this substrate at position P1 Asp causes continuous fluorescent assay monitored at emission wavelength of 393 nM. Furthermore, caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis.
            Literature Reference:M. Enari et al., Nature, 380, 723 (1996)
            Cas:[189696-01-3]
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