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            目錄肽產品
            ADRM-007A
            Pro-Adrenomedullin (N-20), human
            Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2
            Size:0.5
            P1(RMB):552
            MW:2460.9
            One letter sequence:ARLDVASEFRKKWNKWALSR-NH2
            Molecular Formula:C112H178N36O27
            Description:Precursor of adrenomedullin containing proadrenomedullin NH2-terminal 20 peptide (PAMP), a unique 20-residue sequence. When administered, PAMP produces a strong and rapid hypotensive effect in anesthetized rats. PAMP has also been suggested to function as an inhibitory modulator of renal noradrenergic neurotransmission, thereby playing an important role in the regulation of renal functions. PAMP has been proposed to serve as an inhibitory regulator in adrenal catecholamine release in vivo and possesses a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.
            Literature Reference:K. Kitamura et al., BBRC, 194, 720 (1993)
            Cas:[150238-87-2]
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