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            目錄肽產品
            SIGN-009
            JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide
            Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg
            Size:1
            P1(RMB):662
            MW:2107.4
            One letter sequence:CDDYYYGFGCNKFCRPR
            Molecular Formula:
            Description:This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-κB activation.
            Literature Reference:Nickoloff, B. et al. Cell Death Different. 9, 842 (2002).
            Cas:
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