Size：5
P1(RMB)：1090
MW：1739.95
One letter sequence：SFLLRNPNDKYEPF
Molecular Formula：C81H118N20O23
Description：This peptide is a 14-amino acid peptide mimicking the potent thrombin receptor activator as well as an effective agonist for platelet activation.\n This peptide is the fragment 42-55 of the human thrombin receptor and fully reproduces the action of thrombin on MMPs in vascular endothelial cells. This peptide (TRP-14) may signal a variety of thrombin’s responses and has been shown to cause platelet aggregation that can evoke a wide range of G-protein dependent responses.
Literature Reference：T.-K.H.Vu et al., Cell, 64, 1057 (1991)\nY.Maruyama et al., Biochem. Biophys. Res. Commun., 199, 1262 (1994)\nDuhamel-Clérin, E. et al. Arterioscler. Thromb. Vasc. Biol. 17, 1931 (1997); Vassallo, R. et al. J. Biol. Chem. 267, 6081 (1992); Y. Sugama and AB. Malik. Circ. Res. 71, 1015 (1992).
Cas：137339-65-2