目錄肽產(chǎn)品
ENFU-001B
Enfuvirtide
Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
Size：5
P1(RMB)：2190
MW：4491.94
One letter sequence：Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2
Molecular Formula：C204H301N51O64
Description：HIV binds to the host CD4+ cell receptor via the viral protein gp120; gp41. Enfuvirtide binds to gp41 preventing the conformational changes in gp41 which is necessary for fusion of the virus with the cell.
Literature Reference：H.B.Fung and Y.Guo, Clin. Ther., 26, 352 (2004)\nR.Manfredi and S.Sabbatani, Curr. Med. Chem., 13, 2369 (2006)\nJ.Ruof et al., Clin. Drug Investig., 27, 469 (2007)\nA.Streinu-Cercel et al., HIV Clin. Trials, 9, 375 (2008)\n
Cas：159519-65-0
P1(RMB)：2190
MW：4491.94
One letter sequence：Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2
Molecular Formula：C204H301N51O64
Description：HIV binds to the host CD4+ cell receptor via the viral protein gp120; gp41. Enfuvirtide binds to gp41 preventing the conformational changes in gp41 which is necessary for fusion of the virus with the cell.
Literature Reference：H.B.Fung and Y.Guo, Clin. Ther., 26, 352 (2004)\nR.Manfredi and S.Sabbatani, Curr. Med. Chem., 13, 2369 (2006)\nJ.Ruof et al., Clin. Drug Investig., 27, 469 (2007)\nA.Streinu-Cercel et al., HIV Clin. Trials, 9, 375 (2008)\n
Cas：159519-65-0
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